Characterizing Exposure of Veterans to Agent Orange and Other Herbicides Used in Vietnam

Scientific Considerations Regarding a Request for Proposals for Research

Publisher: National Academies Press
ISBN: 9780309057318
eISBN Pdf: 9780309590259
Place of publication: United States
Year of digital publication: 1997
Month: April
Pages: 63
DDC: 616
Language: English

Characterizing Exposure of Veterans to Agent Orange and Other Herbicides Used in Vietnam
Copyright
Contents
Charaterizing Exposure of Veterans to Agent Orange and Other Herbicides Used in Veitnam: Scientific Considerations…
- INTRODUCTION
- BACKGROUND
- RFP STATEMENT OF WORK
- SUPPLEMENTAL INFORMATION
- BACKGROUND ON METHODS
  - Epidemiologic Study Designs
  - Past Exposure Assessment
- AVAILABLE DATA
- POTENTIAL APPROACHES
- VALIDATION OF EXPOSURE ASSESSMENT APPROACHES
- EVALUATION CRITERIA
  - Context (10%)
  - Technical Merit (35%)
  - Feasibility and Validation (25%)
  - Personnel and Experience (20%)
  - Cost and Timeline (10%)
- RESEARCH PRODUCTS
- REFERENCES
APPENDIX The Assessment of Exposure to Herbicides Among Vietnam Veterans: A Review and Recommendations for Future Studies
- ABSTRACT
  - INTRODUCTION
  - HERBICIDE USE IN VIETNAM
    - The Military Experience in Vietnam
    - Military Use of Herbicides in Vietnam
      - Operation Ranch Hand
      - Non-Ranch Hand Spraying of Herbicides
    - Geographical Distribution of Herbicide Sprays
  - EXPOSURE ASSESSMENT IN STUDIES OF VIETNAM VETERANS
    - Self-Reports
  - Records-Based Measures
    - Vietnam Service
      - Branch of Service
      - Combat Experience
      - Military Occupation
  - NEW APPROACHES TO EXPOSURE ASSESSMENT FROM OCCUPATIONAL EPIDEMIOLOGY AND INDUSTRIAL HYGIENE
  - RECONSTRUCTING ESTIMATED EXPOSURE FROM TROOP LOCATION AND HERBICIDESPRAY DATA
  - Records-Based Measures
    - The CDC Exposure Opportunity Index
      - The CDC Agent Orange Study
      - The Stellmans' Study
      - Ranch Hand Exposure Index
  - Biomarkers of Exposure in Vietnam
    - Biomarkers for TCDD
      - Other Dioxin Congeners
      - Chloracne as a Biomarker
      - CDC Agent Orange Validation Study
  - CONCLUSIONS AND RECOMMENDATIONS
  - Development of the Exposure Reconstruction Model
  - Evaluation of the Exposure Reconstruction Model
  - REFERENCES