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A Review of the Department of Defense's Program for Breast Cancer Research

A Review of the Department of Defense's Program for Breast Cancer Research

  • Editor: National Academies Press
  • ISBN: 9780309057806
  • eISBN Pdf: 9780309590525
  • eISBN Epub: 9780309174565
  • Lloc de publicació:  United States
  • Any de publicació digital: 1997
  • Mes: Juliol
  • Pàgines: 151
  • DDC: 616
  • Idioma: Anglés

According to current statistical data, one in eight women will be diagnosed with breast cancer. The five-year survival rate for breast cancer patients has improved in recent years, but the overall mortality rates have changed little. In 1993 Congress allocated $210 million for breast cancer research as part of the Department of Defense budget. An Institute of Medicine (IOM) committee was convened at that time to advise the U.S. Army Medical Research and Development Command on strategies for managing a breast cancer research program. This book evaluates the program's management and achievements to date. Although it is too early to evaluate the program in terms of breakthrough results and new insights produced by the funded projects or investigators, this book documents the process used to select research proposals for funding and analyzes the portfolio of funded projects in terms of their responsiveness to the recommendations and fundamental questions articulated in the 1993 IOM report.

  • A Review of the Department of Defense's Program for Breast Cancer Research
  • Copyright
  • Preface
  • Contents
  • Executive Summary
    • CHARGE TO THE COMMITTEE
    • THE ARMY'S BREAST CANCER RESEARCH PROGRAM
    • METHODS
    • FINDINGS
      • The Army's Breast Cancer Research Program Operation
      • The Breast Cancer Research Program Portfolio
      • Support for Breast Cancer Research Other Than the Army's Program
      • Research Advances and Opportunities
    • CONCLUSIONS
    • RECOMMENDATIONS RELATED TO PROGRAM ACHIEVEMENT AND MANAGEMENT
    • RECOMMENDATIONS FOR FUTURE RESEARCH DIRECTIONS
  • 1 Introduction
    • THE ARMY BREAST CANCER RESEARCH PROGRAM
    • CHARGE TO THE 1997 IOM COMMITTEE
    • RESOURCES AND METHODS USED FOR THIS REPORT
  • 2 Breast Cancer: Biology and Medicine
    • INCIDENCE AND MORTALITY
    • STAGES OF BREAST CANCER DEVELOPMENT
    • BREAST CANCER GENETICS
    • OTHER RISK FACTORS
    • BREAST IMAGING, TREATMENT, AND PREVENTION
      • Breast Imaging
      • Treatment
      • Prevention
    • SOCIAL AND PSYCHOLOGICAL ASPECTS
  • 3 Non-BCRP Support for Breast Cancer Research
    • PUBLISHED LITERATURE
    • FUNDING FROM THE FEDERAL GOVERNMENT
      • Non-BCRP Department of Defense Programs
      • Other Federal Entities (Excluding Department of Health and Human Services)
      • Department of Health and Human Services
        • The National Cancer Institute
        • Other NIH Institutes
        • Other DHHS Agencies
      • National Action Plan on Breast Cancer
    • THE CALIFORNIA BREAST CANCER RESEARCH PROGRAM
    • PRIVATE FOUNDATIONS
      • American Cancer Society
      • Susan G. Komen Foundation
      • Other Philanthropic Organizations
    • NATIONAL PROFESSIONAL ORGANIZATIONS AND SOCIETIES
    • PHARMACEUTICAL INDUSTRY
  • 4 U.S. Army Breast Cancer Research Program
    • HISTORICAL OVERVIEW
    • IOM PROGRAMMATIC VISION (1993)
      • Two-Tiered Review Process
      • Program Administration and Management
    • BCRP IMPLEMENTATION, 1993-1996
      • Scientific Oversight
      • The Integration Panel
        • Executive Committee
        • Programmatic Goals
    • THE REVIEW PROCESS
      • Tier 1: Scientific Peer Review
      • Tier 2: Programmatic Review
      • Consumer Participation
      • Award Negotiation and Processing
      • Monitoring and Evaluation of Progress
  • 5 The Funded Portfolio of the 1993/1994 and 1995 BCRP Award Cycles
    • RESEARCH PROJECTS
    • INFRASTRUCTURE ENHANCEMENT
    • TRAINING AND RECRUITMENT
      • Breast Cancer Centers and Mammography/Breast Imaging Projects
      • Historically Black Colleges and Universities/Minority Institutions
      • Opportunities for Minorities and Women
    • FUNDING FOR PROGRAM ADMINISTRATION
    • DISTRIBUTION OF AWARDS AMONG RESEARCH AREAS
  • 6 Critique
    • ORGANIZATIONAL STRUCTURE AND PROGRAM OVERSIGHT
    • APPLICATION PROCESS
    • SCIENTIFIC PEER REVIEW
    • PROGRAMMATIC REVIEW
    • AWARD NEGOTIATION AND PROCESSING
    • MONITORING AND EVALUATION OF PROGRESS
    • CONSUMER PARTICIPATION
    • FUNDED PORTFOLIO
  • 7 Conclusions and Recommendations
    • CONCLUSIONS
    • RECOMMENDATIONS RELATED TO PROGRAM ACHIEVEMENT AND MANAGEMENT
      • Major Recommendations
      • Other Recommendations
    • RECOMMENDATIONS FOR FUTURE RESEARCH DIRECTIONS
  • References
  • APPENDIX A Individuals Who Provided Testimony to the Committee
    • USAMRMC
    • BCRP SUPPORT
    • BREAST CANCER FUNDING INSTITUTIONS
    • PEER REVIEW ORGANIZATIONS
    • BCRP EXECUTIVE SECRETARIES
    • CONSUMER ORGANIZATIONS/ADVOCACY GROUPS
    • INTEGRATION PANEL MEMBERS
    • OTHER IOM STAFF
  • APPENDIX B Individuals Who Provided Written Responses to Committee Questions
    • PROFESSIONAL SOCIETIES
    • EXECUTIVE SECRETARIES
    • CONSUMER GROUPS
  • APPENDIX C ''Dear Colleague" Letter
  • APPENDIX D Responses to "Dear Colleague" Letter
  • APPENDIX E Tissue Bank Letter and Questionnaire
  • Glossary and Acronyms
  • Biographical Sketches

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