"Refer to the Red Book." That's been the watchword for generations of healthcare professionals seeking trustworthy guidance on pediatric infectious disease prevention, management, and control Now the 32nd edition continues this tradition of excellence with the latest clinical guidance on the manifestations, etiology, epidemiology, diagnosis and treatment of more than 200 childhood infectious diseases.
The 32nd edition provides evidence-based guidance on pediatric infections and vaccinations based on the recommendations of the committee as well as the combined expertise of the CDC, FDA, and hundreds of physician contributors.
Red Book® is an indispensable reference for pediatricians and pediatric infectious disease specialists and is useful for family medicine and emergency medicine physicians as well. Public health and school health professionals, medical residents, and students also will find it a high-yield source of pediatric infectious disease and vaccine information.
- Summary of Major Changes in the 2021 Red Book
- Section 1: Active and Passive Immunization
- Prologue
- Sources of Information About Immunization
- Discussing Vaccines With Patients and Parents
- Addressing Parents’ Questions About Vaccine Safety and Effectiveness
- Common Misconceptions About Immunizations
- Resources for Optimizing Communications With Parents About Vaccines
- Parental Refusal of Immunizations
- Immunization Documentation
- Active Immunization
- Vaccine Ingredients
- Vaccine Handling and Storage
- Vaccine Administration
- Managing Injection Pain
- Immunization Schedule and Timing of Vaccines
- Minimum Ages and Minimum Intervals Between Vaccine Doses
- Interchangeability of Vaccine Products
- Simultaneous Administration of Multiple Vaccines
- Combination Vaccines
- Lapsed Immunizations
- Unknown or Uncertain Immunization Status
- Vaccine Dose
- Active Immunization After Receipt of Immune Globulin or Other Blood Products
- Vaccine Safety
- Risks and Adverse Events
- National Academy of Medicine Reviews of Adverse Events After Immunization
- Immunization Safety Review
- Childhood Immunization Schedule and Safety
- Vaccine Adverse Event Reporting System
- Vaccine Safety Datalink Project
- FDA CBER Sentinel Program
- Clinical Immunization Safety Assessment (CISA) Project
- Vaccine Injury Compensation
- Hypersensitivity Reactions After Immunization
- Immediate-Type Allergic Reactions
- Delayed-Type Allergic Reactions
- Other Vaccine Reactions
- Passive Immunization
- Immune Globulin Intramuscular (IGIM)
- Immune Globulin Intravenous (IGIV)
- Immune Globulin Subcutaneous (IGSC)
- Treatment of Anaphylactic Reactions
- Immunization in Special Clinical Circumstances
- Immunization in Preterm and Low Birth Weight Infants
- Immunization in Pregnancy
- Immunization and Other Considerations in Immunocompromised Children
- Immunization in Children With a Personal or Family History of Seizures
- Immunization in Children With Chronic Diseases
- Immunization in American Indian/Alaska Native Children
and Adolescents
- Immunization in Adolescent and College Populations
- Immunization in Health Care Personnel
- Children Who Received Immunizations Outside the United States or Whose Immunization Status is Unknown or Uncertain
- International Travel
- Section 2: Recommendations for Care of Children in Special Circumstances
- Breastfeeding and Human Milk
- AAP Recommendations on Breastfeeding
- Contraindications to Breastfeeding
- Immunization of Mothers and Infants
- Transmission of Infectious Agents via Human Milk
- Antimicrobial Agents and Other Drugs in Human Milk
- Anti-TNF Biologic Response Modifiers in Human Milk
- Children in Group Child Care and Schools
- Modes of Spread of Infectious Diseases
- Respiratory Tract Diseases
- Enteric Diseases
- Bloodborne Infections
- Other Infections
- Management and Prevention of Infectious Diseases
- Immunization
- Infection Control and Prevention
- Exclusion and Return to Care
- Infection Prevention and Control for Hospitalized Children
- Infection Prevention and Control Precautions
- Strategies to Prevent Health Care-Associated Infections
- Occupational Health
- Sibling Visitation
- Adult Visitation
- Pet Visitation
- Infection Prevention and Control in Ambulatory Settings
- Sexually Transmitted Infections in Adolescents and Children
- STIs During Preventive Health Care of Adolescents
- Sexual Assault and Abuse in Children and Adolescents/Young Adults
- Medical Evaluation for Infectious Diseases for Internationally Adopted, Refugee, and Immigrant Children
- Consideration for Testing for Infectious Agents
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Intestinal Pathogens
- Tissue Parasites/Eosinophilia
- Sexually Transmitted Infections
- Tuberculosis
- HIV Infection
- Chagas Disease (American Trypanosomiasis)
- Other Infectious Diseases
- Injuries From Needles Discarded in the Community
- Wound Care and Tetanus Prophylaxis
- Bloodborne Pathogens
- Preventing Needlestick Injuries
- Bite Wounds
- Prevention of Mosquitoborne and Tickborne Infections
- General Protective Measures
- Repellents for Use on Skin
- Tick Inspection and Removal
- Other Preventive Measures
- Prevention of Illnesses Associated with Recreational Water Use
- Section 3: Summaries of Infectious Diseases
- Actinomycosis
- Adenovirus Infections
- Amebiasis
- Amebic Meningoencephalitis and Keratitis
- Anthrax
- Arboviruses
- Arcanobacterium haemolyticum Infections
- Ascaris lumbricoides Infections
- Aspergillosis
- Astrovirus Infections
- Babesiosis
- Bacillus cereus Infections and Intoxications
- Bacterial Vaginosis
- Bacteroides, Prevotella, and Other Anaerobic Gram-NegativeBacilli Infections
- Balantidium coli Infections (Balantidiasis)
- Bartonella henselae (Cat-Scratch Disease)
- Baylisascaris Infections
- Infections With Blastocystis Species
- Blastomycosis
- Bocavirus
- Borrelia Infections Other Than Lyme Disease (Relapsing Fever)
- Brucellosis
- Burkholderia Infections
- Campylobacter Infections
- Candidiasis
- Chancroid and Cutaneous Ulcers
- Chikungunya
- Chlamydial Infections
- Chlamydia pneumoniae
- Chlamydia psittaci (Psittacosis, Ornithosis, Parrot Fever)
- Chlamydia trachomatis
- Clostridial Infec
- Botulism and Infant Botulism (Clostridium botulinum)
- Clostridial Myonecrosis (Gas Gangrene)
- Clostridioides difficile (formerly Clostridium difficile)
- Clostridium perfringens Foodborne Illness
- Coccidioidomycosis
- Coronaviruses, Including SARS-CoV-2 and MERS-CoV
- Cryptococcus neoformans and Cryptococcus gattii Infections (Cryptococcosis)
- Cryptosporidiosis
- Cutaneous Larva Migrans
- Cyclosporiasis
- Cystoisosporiasis (formerly Isosporiasis)
- Cytomegalovirus Infection
- Dengue
- Diphtheria
- Ehrlichia, Anaplasma, and Related Infections (Human Ehrlichiosis, Anaplasmosis, and Related Infections Attributable to Bacteria in the Family Anaplasmataceae)
- Serious Neonatal Bacterial Infections Caused by Enterobacteriaceae (Including Septicemia and Meningitis)
- Enterovirus (Nonpoliovirus) (Group A and B Coxsackieviruses, Echoviruses, Numbered Enteroviruses)
- Epstein-Barr Virus Infections (Infectious Mononucleosis)
- Escherichia coli Diarrhea (Including Hemolytic-Uremic Syndrome)
- Other Fungal Diseases
- Fusobacterium Infections (Including Lemierre Syndrome)
- Giardia duodenalis (formerly Giardia lamblia and Giardia intestinalis) Infections (Giardiasis)
- Gonococcal Infections
- Granuloma Inguinale (Donovanosis)
- Haemophilus influenzae Infections
- Hantavirus Pulmonary Syndrome
- Helicobacter pylori Infections
- Hemorrhagic Fevers Caused by Arenaviruses
- Hemorrhagic Fevers Caused by Bunyaviruses
- Hemorrhagic Fevers Caused by Filoviruses: Ebola and Marburg
- Hepatitis A
- Hepatitis B
- Hepatitis C
- Hepatitis D
- Hepatitis E
- Herpes Simplex
- Histoplasmosis
- Hookworm Infections (Ancylostoma duodenale and Necator americanus)
- Human Herpesvirus 6 (Including Roseola) and 7
- Human Herpesvirus 8
- Human Immunodeficiency Virus Infection
- Human Papillomaviruses
- Influenza
- Kawasaki Disease
- Kingella kingae Infections
- Legionella pneumophila Infections
- Leishmaniasis
- Leprosy
- Leptospirosis
- Listeria monocytogenes Infections (Listeriosis)
- Lyme Disease (Lyme Borreliosis, Borrelia burgdorferi sensu lato Infection)
- Lymphatic Filariasis (Bancroftian, Malayan, and Timorian)
- Lymphocytic Choriomeningitis Virus
- Malaria
- Measles
- Meningococcal Infections
- Human Metapneumovirus
- Microsporidia Infections (Microsporidiosis)
- Molluscum Contagiosum
- Moraxella catarrhalis Infections
- Mumps
- Mycoplasma pneumoniae and Other Mycoplasma Species Infections
- Nocardiosis
- Norovirus and Sapovirus Infections
- Onchocerciasis (River Blindness, Filariasis)
- Paracoccidioidomycosis (Formerly Known as South American Blastomycosis)
- Paragonimiasis
- Parainfluenza Viral Infections
- Parasitic Diseases
- Parechovirus Infections
- Parvovirus B19 (Erythema Infectiosum, Fifth Disease)
- Pasteurella Infections
- Pediculosis Capitis (Head Lice)
- Pediculosis Corporis (Body Lice)
- Pediculosis Pubis (Pubic Lice, Crab Lice)
- Pelvic Inflammatory Disease
- Pertussis (Whooping Cough)
- Pinworm Infection (Enterobius vermicularis)
- Pityriasis Versicolor (Formerly Tinea Versicolor)
- Plague
- Pneumocystis jirovecii Infections
- Poliovirus Infections
- Polyomaviruses (BK, JC, and Other Polyomaviruses)
- Prion Diseases: Transmissible Spongiform Encephalopathies
- Pseudomonas aeruginosa Infections
- Q Fever (Coxiella burnetii Infection)
- Rabies
- Rat-Bite Fever
- Respiratory Syncytial Virus
- Rhinovirus Infections
- Rickettsial Diseases
- Rickettsialpox
- Rocky Mountain Spotted Fever
- Rotavirus Infections
- Rubella
- Salmonella Infections
- Scabies
- Schistosomiasis
- Shigella Infections
- Smallpox (Variola)
- Sporotrichosis
- Staphylococcal Food Poisoning
- Staphylococcus aureus
- Coagulase-Negative Staphylococcal Infections
- Group A Streptococcal Infections
- Group B Streptococcal Infections
- Non-Group A or B Streptococcal and Enterococcal Infections
- Streptococcus pneumoniae (Pneumococcal) Infections
- Strongyloidiasis (Strongyloides stercoralis)
- Syphilis
- Tapeworm Diseases (Taeniasis and Cysticercosis)
- Other Tapeworm Infections (Including Hydatid Disease)
- Tetanus (Lockjaw)
- Tinea Capitis (Ringworm of the Scalp)
- Tinea Corporis (Ringworm of the Body)
- Tinea Cruris (Jock Itch)
- Tinea Pedis and Tinea Unguium (Onychomycosis) (Athlete’s Foot, Ringworm of the Feet)
- Toxocariasis
- Toxoplasma gondii Infections (Toxoplasmosis)
- Trichinellosis (Trichinella spiralis and Other Species)
- Trichomonas vaginalis Infections (Trichomoniasis)
- Trichuriasis (Whipworm Infection)
- African Trypanosomiasis (African Sleeping Sickness)
- American Trypanosomiasis (Chagas Disease)
- Tuberculosis
- Nontuberculous Mycobacteria (Environmental Mycobacteria, Mycobacteria other than Mycobacterium tuberculosis)
- Tularemia
- Louseborne Typhus (Epidemic or Sylvatic Typhus)
- Murine Typhus (Endemic or Fleaborne Typhus)
- Ureaplasma urealyticum and Ureaplasma parvum Infections
- Varicella-Zoster Virus Infections
- Vibrio Infections
- Cholera (Vibrio cholerae)
- Other Vibrio Infections
- West Nile Virus
- Yersinia enterocolitica and Yersinia pseudotuberculosis Infections (Enteritis and Other Illnesses)
- Zika
- Section 4: Antimicrobial Agents and Related Therapy
- Introduction
- Fluoroquinolones
- Tetracyclines
- Antimicrobial Agents Approved for Use in Adults but Not Children
- Cephalosporin Cross-Reactivity With Other Beta Lactam Antibiotics
- Antimicrobial Resistance and Antimicrobial Stewardship:
Appropriate and Judicious Use of Antimicrobial Agents
- Antimicrobial Resistance
- Factors Contributing to Resistance
- Actions to Prevent or Slow Antimicrobial Resistance
- Antimicrobial Stewardship
- Role of the Medical Provider
- Principles of Appropriate Use of Antimicrobial Therapy for Upper Respiratory Tract Infections
- Drug Interactions
- Tables of Antibacterial Drug Dosages
- Sexually Transmitted Infections
- Antifungal Drugs for Systemic Fungal Infections
- Polyenes
- Pyrimidines
- Azoles
- Echinocandins
- Recommended Doses of Parenteral and Oral Antifungal Drugs
- Topical Drugs for Superficial Fungal Infections
- Non-HIV Antiviral Drugs
- Drugs for Parasitic Infections
- Systems-based Treatment Table
- MedWatch—The FDA Safety Information and Adverse Event-Reporting Program
- Section 5: Antimicrobial Prophylaxis
- Antimicrobial Prophylaxis
- Infection-Prone Body Sites
- Exposure to Specific Pathogens
- Vulnerable Hosts
- Antimicrobial Prophylaxis in Pediatric Surgical Patients
- Guidelines for Appropriate Use
- Indications for Prophylaxis
- Surgical Site Infection Criteria
- Timing of Administration of Prophylactic Antimicrobial Agents
- Dosing and Duration of Administration of Antimicrobial Agents
- Preoperative Screening and Decolonization
- Recommended Antimicrobial Agents
- Prevention of Bacterial Endocarditis
- Neonatal Ophthalmia
- Primary Prevention
- Secondary Prevention
- Legal Mandates for Topical Prophylaxis for Neonatal Ophthalmia
- Pseudomonal Ophthalmia
- Other Nongonococcal, Nonchlamydial Ophthalmia
- Appendices
- I. Directory of Resources
- II. Codes for Commonly Administered Pediatric Vaccines/Toxoids and Immune Globulins
- III. Nationally Notifiable Infectious Diseases in the United States
- IV. Guide to Contraindications and Precautions to Immunizations
- V. Prevention of Infectious Disease From Contaminated Food Products
- VI. Clinical Syndromes Associated With Foodborne Diseases
- VII. Diseases Transmitted by Animals (Zoonoses)
- Index
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