The cornerstone of chemical and biological defense strategy is protection (i.e., insulating personnel from chemical and biological agents using individual clothing ensembles and respirators, as well as collective filtration systems and shelters). The CSC was asked by the CBDCOM to undertake a technology assessment of the Army's MIST program-which is designed to test protective suit ensembles in simulated chemical attacks.
- Technical Assessment of the Man-In-Simulant Test (MIST) Program
- Copyright
- Preface
- Contents
- Acronyms
- Executive Summary
- GENERAL CONCLUSIONS AND RECOMMENDATIONS
- 1 Introduction
- BACKGROUND
- CHARGE TO THE COMMITTEE
- STUDY APPROACH
- 2 Test Protocol
- UNDERLYING CONCEPTS
- Introduction
- Materials Evaluation
- Suit Technology
- Evaluation of Suit Systems
- METHODOLOGY
- Methods for Evaluating Protective Clothing
- MIST Test Procedure
- Body Region Hazard Analysis
- Evaluation of Suits against Exposure to HD (Local Analysis)
- Evaluation of Suits against Exposure to VX (Systemic Analysis)
- 3 Simulant Section
- IMPORTANCE OF DERMAL PENETRATION
- USE OF SIMULANT TO PREDICT DERMAL PENETRATION
- SELECTION OF A SIMULANT
- TOXICITY OF METHYL SALICYLATE
- FINAL CHOICE OF A SIMULANT FOR MIST
- 4 Test Methods and Sampler Selection
- PURPOSES OF MONITORING
- RATIONALE FOR THE SELECTION OF MONITORING METHODS
- CHAMBER MONITORING
- OPTIONS FOR IN-SUIT MONITORING
- Active Sampling Systems
- Overview
- External Pumps and Tubes
- Pumps and Sampling Systems inside the Protective Garment
- Passive Samplers
- Natick Sampler
- 5 Assumptions and Limitations
- TEST PROTOCOL CONSIDERATIONS
- HUMAN FACTORS CONSIDERATIONS
- ACETYLCHOLINESTERASE INHIBITION AS A BIOLOGICAL MARKER
- BIOLOGICAL INTERPRETATION OF THE MIST/BRHA
- 6 Conclusions and Recommendations
- SPECIFIC CONCLUSIONS AND RECOMMENDATIONS
- GENERAL CONCLUSIONS AND RECOMMENDATIONS
- References
- APPENDICES
- Appendix A Body Region Hazard Analysis
- INTRODUCTION
- CONCEPTS
- OPPORTUNITIES AND APPLICATIONS
- NOMENCLATURE
- REFERENCES
- Appendix B Panel and Committee Meetings
- PANEL MEETINGS
- FULL COMMITTEE MEETINGS
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