Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals

Application of Systematic Review Methods in an Overall Strategy for Evaluating Low-Dose Toxicity from Endocrine Active Chemicals

  • Publisher: National Academies Press
  • ISBN: 9780309458627
  • eISBN Pdf: 9780309458634
  • eISBN Epub: 9780309458658
  • Place of publication:  United States
  • Year of digital publication: 2017
  • Month: July
  • Pages: 423
  • Language: English

This book provides the National Academy of Sciences' 1995 review of the technology development program for the remediation of the Department of Energy's weapons complex facilities. It makes scientific, technical, and programmatic recommendations to strengthen technology development within DOE and ensure that it meet its goals of cost effectiveness, safety, and decreased risk. The recommendations address DOE's five focus areas: landfill stabilization; contaminant plume containment and remediation; facility transitioning, decommissioning, and final disposition; mixed waste characterization treatment; and high-level waste in tanks. The book also addresses technologies in areas that cross cut the above focus area programs, namely characterization monitoring and sensor technologies, efficient separations and processing, robotics, and waste disposal.

  • Cover
  • Front Matter
  • Summary
  • 1 Introduction
  • 2 Strategy for Evaluating Low-Dose Effects
  • 3 Phthalates and Male Reproductive-Tract Development
  • 4 Effect of Polybrominated Diphenyl Ethers on Neurodevelopment
  • 5 Lessons Learned and Reflections on the Statement of Task
  • Appendix A: Biosketches of the Committee on Endocrine-Related Low-Dose Toxicity
  • Appendix B: Workshop on Potential Case Studies for Unraveling Endocrine-Related Low-Dose Toxicity
  • Appendix C: Supporting Materials for the Phthalate (Animal) Systematic Review
  • Appendix D: Supporting Materials for the Phthalate (Human) Systematic Review
  • Appendix E: Supporting Materials for the PBDE (Animal) Systematic Review
  • Appendix F: Supporting Materials for the PBDE (Human) Systematic Review

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